Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10
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چکیده
منابع مشابه
Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10.
The UDP-glucuronosyltransferase (UGT) 1A10 is an extra-hepatic enzyme that plays an important role in the glucuronidation of a variety of endogenous and exogenous substances and is expressed throughout the aerodigestive and digestive tracts. Two classes of carcinogens that target the colon, heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons, are known to be detoxified by the UGT fa...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2007
ISSN: 0143-3334,1460-2180
DOI: 10.1093/carcin/bgm164